Regulatory T cells and IFN-γ-producing Th1 cells play a critical role in the pathogenesis of Sjögren's Syndrome
Y.-H. Wang, W. Li, M. McDermott, G.-Y. Son, G. Maiti, F. Zhou, A. Y. Tao, D. Raphael, A. L. Moreira, B. Shen, M. Vaeth, B. Nadorp, S. Chakravarti, R. S. Lacruz, S. Feske
This study identifies Treg cells and IFN-γ-producing Th1 cells as key drivers of Sjögren's Syndrome pathogenesis using a mouse model and single-cell transcriptomics.
bioRxiv · Jan 23, 2024 · PreprintImmunology