Regulation of specific cell clusters in TCR-T cells responding to differential expression of tumor PD-L1
D. Renpeng, S. Liu, H. Chen, B. Kang, R. Drmanac, Y. Gu, X. Dong, Q. Gao
The paper examines how PD-L1 expression on tumor cells affects specific cell clusters in TCR-T cells through single-cell RNA sequencing and cytotoxicity assays.
bioRxiv · Jul 28, 2020Immunology