Author

D. S. Ory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Al-Motawa· 1 shared A. Cross· 1 shared A. Stahl· 1 shared B. Blagg· 1 shared C. A. Berdan· 1 shared D. F. Covey· 1 shared D. Nomura· 1 shared E. Weiss· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

A. Al-Motawa

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Author profile →

2 papers

Recent·Most cited

HSP90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts

N. H. Pipalia, S. Z. Saad, K. Subramanian, A. Cross, A. Al-Motawa, K. K. Garg, B. Blagg, L. Neckers, P. Helquist, O. Wiest, D. S. Ory, F. R. Maxfield

This study shows HSP90 inhibitors reduce cholesterol storage in NPC1 mutant fibroblasts by enhancing mutant NPC1 protein delivery to lysosomes.

bioRxiv · Apr 22, 2021Cell Biology

4 β-hydroxycholesterol is a pro-lipogenic factor that promotes SREBP1c expression and activity through Liver X-receptor.

O. Moldavski, P.-J. H. Zushin, C. A. Berdan, R. J. van Eijkeren, X. Jiang, M. Qian, D. S. Ory, D. F. Covey, D. Nomura, A. Stahl, E. Weiss, R. Zoncu

This study identifies 4β-hydroxycholesterol as a pro-lipogenic factor that activates SREBP1c via LXR to promote de novo lipogenesis.

bioRxiv · Aug 20, 2020Biochemistry