Fibroblasts-derived extracellular vesicles contain SFRP1 and mediate pulmonary fibrosis
O. Burgy, C. H. Mayr, B. Ballester Llobell, A. Sengupta, D. Schenesse, C. Coughlan, T. Parimon, P. Chen, M. Lindner, A. Hilgendorff, M. Mann, A. O. Yildirim, O. Eickelberg, M. Lehmann, H. B. Schiller, , M. Königshoff
This study identifies fibroblast-derived extracellular vesicles containing SFRP1 that contribute to pulmonary fibrosis and suggests SFRP1 as a therapeutic target.
bioRxiv · Dec 22, 2022Cell Biology