Author

D. Steele

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:microscopy & imaging analysis· 3 Research Focus:cell signaling & trafficking· 2 Assay:imaging· 2 Organism:rat· 2 Research Focus:cell type annotation· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

I. Jayasinghe· 3 shared E. White· 2 shared M. E. Hurley· 2 shared T. M. D. Sheard· 2 shared Z. Yang· 2 shared E. Pervolaraki· 1 shared G. Gurrola· 1 shared H. Kirton· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersBiophysics

I. Jayasinghe

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3 papers

Recent·Most cited

Correlative super-resolution analysis of cardiac calcium sparks and their molecular origins in health and disease

M. E. Hurley, E. White, T. M. D. Sheard, D. Steele, I. Jayasinghe

The paper correlates cardiac calcium sparks with RyR clustering patterns using super-resolution microscopy in healthy and failing rat ventricular myocytes, revealing a link between spark properties and RyR organization.

bioRxiv · Feb 12, 2023 · PreprintBiophysics

A super-resolution protocol to correlate structural underpinnings of fast second-messenger signalling in primary cell types

M. E. Hurley, T. M. D. Sheard, R. Norman, H. M. Kirton, S. S. Shah, E. Pervolaraki, Z. Yang, N. Gamper, E. White, D. Steele, I. Jayasinghe

The paper describes a correlative imaging protocol to visualize calcium signals and ryanodine receptors at nanoscale resolution in primary cells.

bioRxiv · Sep 29, 2020Biophysics

Peptide ligands of the cardiac ryanodine receptor as super-resolution imaging probes

T. Sheard, J. Colyer, I. Jayasinghe, H. Valdivia, L. Howlett, H. Kirton, Z. Yang, D. Steele, G. Gurrola

The paper investigates peptide ligands of the cardiac ryanodine receptor as super-resolution imaging probes, finding that they label non-specific structures in cardiomyocytes.

bioRxiv · Jun 26, 2020 · PreprintCell Biology