BiochemistrybioRxiv
Substrate Channeling via a Transient Protein-Protein Complex: The case of D-Glyceraldehyde-3-Phosphate Dehydrogenase and L-Lactate Dehydrogenase
Z. M. Svedruzic, I. Odorcic, C. H. Chang, D. Svedruzic
The paper investigates substrate channeling between GAPDH and LDH enzymes, showing that NADH channeling occurs via a transient complex and is influenced by NADH concentration and protein interactions.
DOI 10.1038/s41598-020-67079-2