Author

C. H. Chang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. B. Pine· 1 shared A. Day· 1 shared A. E. Gelman· 1 shared A. H. Kim· 1 shared A. I. Lee· 1 shared A. M. Rauseo· 1 shared C. Price· 1 shared C. S. Dela Cruz· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. B. Pine

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2 papers

Recent·Most cited

ImmunologybioRxivFeb 22, 2021

Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection.

L. Ma, S. K. Sahu, M. Cano…·H. S. Kulkarni

The paper shows that complement activation is higher in severe SARS-CoV-2 infection compared to influenza and non-COVID respiratory failure, with the alternative pathway linked to worse outcomes.

DOI 10.1126/sciimmunol.abh2259

humanproteomics

𝕏 PostBluesky

BiochemistrybioRxivJan 22, 2020

Substrate Channeling via a Transient Protein-Protein Complex: The case of D-Glyceraldehyde-3-Phosphate Dehydrogenase and L-Lactate Dehydrogenase

Z. M. Svedruzic, I. Odorcic, C. H. Chang, D. Svedruzic

The paper investigates substrate channeling between GAPDH and LDH enzymes, showing that NADH channeling occurs via a transient complex and is influenced by NADH concentration and protein interactions.

DOI 10.1038/s41598-020-67079-2

experimental assay

𝕏 PostBluesky