D. T. Ting

This study uses single cell spatial transcriptomics to show LINE1 repeat RNA expression in HCC correlates with a disorganized immune microenvironment and poor patient survival.

This study uses single-cell spatial transcriptomics and optimal transport analysis to reveal therapy-induced changes in pancreatic cancer microenvironment interactions.

This study shows pancreatic tumors co-evolve with retrotransposons to modulate immune responses by regulating viral mimicry through SINEs and L1 retrotransposition.

This paper integrates single-cell RNA sequencing data with organoid co-cultures to study inflammatory signaling in pancreatic cancer and validates findings through transfer learning and mechanistic experiments.

The paper uses single cell proteomics to identify kinase activity differences in tumor compartments, showing how they affect sensitivity to mTOR-PI3K inhibition.

The paper quantifies repeat element polarization in cancer transcriptomes to identify biomarkers for immunotherapy response and tumor microenvironment immunosuppression.