Author

E. You

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. D. Gioacchino· 1 shared A. Karacay· 1 shared A. Solovyov· 1 shared B. D. Greenbaum· 1 shared B. Dickson· 1 shared C. A. Iacobuzio-Donahue· 1 shared D. D. Carvalho· 1 shared D. Hoyos· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. D. Gioacchino

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer cells co-evolve with retrotransposons to mitigate viral mimicry

S. Sun, J. Hong, E. You, K. M. Tsanov, J. Chacon-Barahona, A. D. Gioacchino, D. Hoyos, H. Li, H. Jiang, H. Ly, S. A. Marhon, R. Murali, P. Chanda, A. Karacay, N. Vabret, , B. D. Greenbaum

This study shows pancreatic tumors co-evolve with retrotransposons to modulate immune responses by regulating viral mimicry through SINEs and L1 retrotransposition.

bioRxiv · May 19, 2023 · PreprintCancer Biology

Molecular mechanisms of fentanyl mediated β-arrestin biased signaling

P. W. de Waal, J. Shi, E. You, X. Wang, K. Melcher, Y. Jiang, H. E. Xu, B. Dickson

This paper investigates how fentanyl activates the mu-opioid receptor through beta-arrestin biased signaling using molecular dynamics simulations and validates findings with synthesized compounds.

PLOS Computational Biology · Apr 10, 2020Peer-reviewedBiophysics

YAP nuclear translocation through dynein and acetylated microtubule controls fibroblast activation.

S. Rhee, E. You, P. Ko, J. Jeong, S. Keum, J.-W. Kim, Y.-J. Seo, W. K. Song

This study shows that YAP nuclear translocation via dynein and acetylated microtubules promotes myofibroblast differentiation in soft substrates, enhancing TGF-β1-induced Smad activity.

bioRxiv · Jul 4, 2019 · PreprintCell Biology