Co-ordinated Ras and Rac activity shapes macropinocytic cups and enables phagocytosis of geometrically diverse bacteria
C. M. Buckley, H. Pots, A. Gueho, B. A. Phillips, B. Gilsbach, D. Traynor, A. Nikolaev, T. Soldati, A. J. Parnell, A. Kortholt, J. S. King
This study shows that RGBARG coordinates Ras and Rac activity to shape macropinocytic cups and enable phagocytosis of geometrically diverse bacteria in Dictyostelium discoideum.
bioRxiv · Oct 17, 2019Cell Biology