Cancer BiologybioRxivPreprint
Single-cell molecular profiling using ex vivo functional readouts fuels precision oncology in glioblastoma
D. Panovska, P. Nazari, B. Cole…·F. De Smet
The paper introduces PROSPERO, a single-cell assay to evaluate therapy response in glioblastoma by measuring molecular drug responses in fresh tumor samples, revealing limited therapeutic capacity and cellular plasticity.
DOI 10.1101/2022.10.17.512525