Author

D. VanInsberghe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:bacteria (other)· 1 Research Focus:clustering· 1 Research Focus:phylogenetics / evolution· 1 Organism:plant (other)· 1

Frequent Co-Authors

A. C. Lowen· 4 shared K. E. Holmes· 2 shared K. Koelle· 2 shared L. M. Ferreri· 2 shared A. Bowman· 1 shared A. J. French· 1 shared A. J. Prussin· 1 shared A. S. Neish· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersMicrobiology

A. C. Lowen

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Ventilation does not affect influenza virus transmission efficiency in a ferret playpen setup

N. C. Rockey, V. Le Sage, M. Shephard, N. Vargas-Maldonado, A. J. French, S. Walter, L. M. Ferreri, K. E. Holmes, D. VanInsberghe, H. Clack, A. J. Prussin, A. C. Lowen, L. Marr, S. Lakdawala

This study shows that ventilation rates do not affect influenza virus transmission efficiency in a ferret playpen setup with close-range interactions and fomites.

bioRxiv · Dec 26, 2023 · PreprintMicrobiology

Viral expansion after transfer is a primary driver of influenza A virus transmission bottlenecks

K. E. Holmes, D. VanInsberghe, L. M. Ferreri, B. Elie, K. Ganti, C.-Y. Lee, A. C. Lowen

This study identifies viral expansion after transfer as a key factor in influenza A virus transmission bottlenecks, showing that diversity declines rapidly post-infection.

bioRxiv · Nov 19, 2023Microbiology

Genetic drift and purifying selection shape within-host influenza A virus populations during natural swine infections

D. VanInsberghe, D. S. McBride, J. DaSilva, T. J. Stark, M. S. Y. Lau, S. S. Shepard, J. R. Barnes, A. Bowman, A. C. Lowen, K. Koelle

This study examines within-host influenza A virus diversity and evolution in swine, finding low genetic diversity and evidence of purifying selection and genetic drift.

bioRxiv · Oct 23, 2023Evolutionary Biology

Rapid evolutionary turnover of mobile genetic elements drives microbial resistance to viruses

F. A. Hussain, J. Dubert, J. Elsherbini, M. Murphy, D. VanInsberghe, P. Arevalo, K. Kauffman, B. Kotska Rodino-Janeiro, M. Polz

The paper shows that mobile genetic elements rapidly evolve to confer phage resistance in bacteria, with resistance unlinked to other genomic features.

bioRxiv · Mar 26, 2021Microbiology

Recombinant SARS-CoV-2 genomes are currently circulating at low levels

D. VanInsberghe, A. S. Neish, A. C. Lowen, K. Koelle

The paper identifies 1175 putative recombinant SARS-CoV-2 genomes from over 537,000 sequences, estimates they make up at most 5% of circulating viruses in the USA and UK, and highlights substitutions of concern in some recombinants.

bioRxiv · Aug 5, 2020Evolutionary Biology