PhysiologybioRxiv
Enteroendocrine cells sense bacterial tryptophan catabolites to activate enteric and vagal neuronal pathways
L. Ye, M. Bae, C. D. Cassilly…·J. F. Rawls
This study identifies a molecular pathway by which enteroendocrine cells respond to bacterial tryptophan catabolites, activating enteric and vagal neurons through Trpa1 signaling.
DOI 10.1016/j.chom.2020.11.011