Author

D. Winkelmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

B. Virok· 1 shared C. Risi· 1 shared C. Scarff· 1 shared D. P. Klebl· 1 shared E. Forgacs· 1 shared E. M. Ostap· 1 shared F. Sobott· 1 shared H. D. White· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

B. Virok

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2 papers

Recent·Most cited

Swinging lever mechanism of myosin directly demonstrated by time-resolved cryoEM

D. P. Klebl, S. N. McMillan, C. Risi, E. Forgacs, B. Virok, J. Atherton, M. Stofella, D. Winkelmann, F. Sobott, V. Galkin, P. J. Knight, S. P. Muench, C. Scarff, H. D. White

This paper uses time-resolved cryoEM to directly observe the swinging lever mechanism of myosin-5, showing its structural changes during ATP hydrolysis and force generation.

bioRxiv · Jan 5, 2024 · PreprintBiochemistry

Single molecule mechanics resolves the earliest events in force generation by cardiac myosin

M. Woody, M. Capitanio, D. Winkelmann, E. M. Ostap, Y. E. Goldman

This study uses ultra-high-speed optical traps to observe rapid mechanical events in cardiac myosin, showing the working stroke occurs before phosphate release and is influenced by force.

bioRxiv · Jun 27, 2019Biochemistry