Heterogeneity in clone dynamics within and adjacent to intestinal tumours identified by Dre-mediated lineage tracing
A.-S. K. Thorsen, D. Khamis, R. Kemp, M. Colombe, F. C. Lourenco, E. Morrissey, D. Winton
The paper uses Dre-mediated lineage tracing to study clone dynamics in intestinal tumours and adjacent tissue, revealing heterogeneous clonal expansion patterns and a zone of inhibited clone growth near tumours.
bioRxiv · May 13, 2020Cancer Biology