Author

A. Hoyle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 4 Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:human· 5 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. M. Piskorz· 2 shared A. Pickard· 2 shared D. Ennis· 2 shared D. Millan· 2 shared I. A. McNeish· 2 shared J. D. Brenton· 2 shared J. Swift· 2 shared K. E. Kadler· 2 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. M. Piskorz

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Collagen fibril formation at the plasma membrane occurs independently from collagen secretion

A. Pickard, R. Garva, A. D. Adamson, B. C. Calverley, A. Hoyle, C. Hayward, D. Spiller, Y. Lu, N. W. Hodson, O. Mandolfo, K. Kim, G. Bou-Charios, J. Swift, B. Bigger, K. E. Kadler

The paper investigates collagen fibril formation in fibroblasts, showing it occurs at the plasma membrane independently of secretion and involves endocytosis.

bioRxiv · May 9, 2024Cell Biology

Optimising a self-assembling peptide hydrogel as a Matrigel alternative for 3-dimensional mammary epithelial cell culture

E. Lingard, S. Dong, A. Hoyle, E. Appleton, A. Hales, E. Skaria, C. Lawless, A. Miller, M. Domingos, A. Saiani, J. Swift, A. P. Gilmore

This study optimizes self-assembling peptide hydrogels to better support mammary epithelial cell organoid formation compared to Matrigel.

bioRxiv · Sep 15, 2023Cell Biology

Molecular landscape and functional characterization of centrosome amplification in ovarian cancer

C. M. Sauer, J. A. Hall, D.-L. Couturier, T. Bradley, A. M. Piskorz, J. Griffiths, A. Sawle, M. D. Eldridge, P. Smith, K. Hosking, M. A. Reinius, L. Morrill Gavarro, A.-M. Mes-Masson, D. Ennis, D. Millan, , J. D. Brenton

This study identifies centrosome amplification as a common and heterogeneous feature in HGSOC, linked to CIN and treatment resistance.

bioRxiv · Sep 13, 2022Cancer Biology

Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis

J. CHANG, A. PICKARD, J. A. Herrera, S. O'Keefe, M. Hartshorn, R. GARVA, A. Hoyle, L. Dingle, C. Zeltz, J. Wong, A. Reid, R. V. Venkateswaran, Y. Lu, P. Caswell, S. High, , K. E. KADLER

This study shows that circadian-regulated endocytic recycling is essential for collagen fibril assembly and is disrupted in fibrosis.

bioRxiv · Mar 25, 2021Cell Biology

Phospho-regulation of Atoh1 is required for plasticity of secretory progenitors and tissue regeneration

G. Tomic, E. Morrissey, S. Kozar, S. Ben-Moshe, A. Hoyle, R. Azzarelli, R. Kemp, C. S. R. Chilamakuri, S. Itzkovitz, A. Philpott, D. Winton

This study shows that phosphorylation of Atoh1 is essential for secretory progenitor plasticity and tissue regeneration in the intestine.

bioRxiv · Feb 26, 2018Cell Biology

Copy-number signatures and mutational processes in ovarian carcinoma

G. Macintyre, T. Goranova, D. De Silva, D. Ennis, A. M. Piskorz, M. Eldridge, D. Sie, L.-A. Lewsley, A. Hanif, C. Wilson, S. Dowson, R. M. Glasspool, M. Lockley, E. Brockbank, A. Montes, , J. D. Brenton

This study identifies copy-number signatures in ovarian cancer and links them to mutational processes, showing that most cases involve multiple processes, suggesting therapeutic challenges.

bioRxiv · Sep 4, 2017Cancer Biology