Author

R. Kemp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2 Animal Behavior & Cognition· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:differential expression· 3 Research Focus:cell-cell communication· 2 Research Focus:clustering· 2 Organism:human· 2 Assay:imaging· 2 Organism:mouse· 2

Frequent Co-Authors

E. Morrissey· 3 shared C. S. R. Chilamakuri· 2 shared D. J. Winton· 2 shared D. Winton· 2 shared F. Perrone· 2 shared M. Zilbauer· 2 shared N. Skoufou-Papoutsaki· 2 shared S. Adler· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

E. Morrissey

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

PTEN and ARID1A haploinsufficiency equip colonic epithelium for oncogenic transformation

N. Skoufou-Papoutsaki, S. Adler, S. Mehmed, C. Tume, C. Olpe, E. Morrissey, R. Kemp, A.-C. Girard, E. B. Moutin, C. S. R. Chilamakuri, J. L. Miller, C. Lindskog, F. Werle, K. Marks, F. Perrone, , D. J. Winton

The paper investigates how PTEN and ARID1A haploinsufficiency in colonic epithelium contributes to oncogenic transformation by altering clone dynamics and creating a pro-tumorigenic microenvironment.

bioRxiv · Mar 27, 2024 · PreprintCancer Biology

Efficient genetic editing of human intestinal organoids using ribonucleoprotein-based CRISPR

N. Skoufou-Papoutsaki, S. Adler, P. D'Santos, L. Mannion, S. Mehmed, R. Kemp, A. Smith, F. Perrone, K. Nayak, A. Russell, M. Zilbauer, D. J. Winton

This study develops an efficient ribonucleoprotein-based CRISPR method for editing human intestinal organoids, achieving 98% editing efficiency with no off-target effects and revealing PTEN loss phenotypes.

bioRxiv · Mar 31, 2023 · PreprintCell Biology

Wing tags severely impair movement in African Cape Vulture

T. Curk, M. Scacco, K. Safi, M. Wikelski, W. Fiedler, R. Kemp, K. Wolter

This study shows that wing tags impair flight performance in Cape Vultures, leading to reduced flight frequency, slower speeds, and shorter distances traveled compared to leg bands.

bioRxiv · Aug 28, 2020Animal Behavior & Cognition

Heterogeneity in clone dynamics within and adjacent to intestinal tumours identified by Dre-mediated lineage tracing

A.-S. K. Thorsen, D. Khamis, R. Kemp, M. Colombe, F. C. Lourenco, E. Morrissey, D. Winton

The paper uses Dre-mediated lineage tracing to study clone dynamics in intestinal tumours and adjacent tissue, revealing heterogeneous clonal expansion patterns and a zone of inhibited clone growth near tumours.

bioRxiv · May 13, 2020Cancer Biology

Phospho-regulation of Atoh1 is required for plasticity of secretory progenitors and tissue regeneration

G. Tomic, E. Morrissey, S. Kozar, S. Ben-Moshe, A. Hoyle, R. Azzarelli, R. Kemp, C. S. R. Chilamakuri, S. Itzkovitz, A. Philpott, D. Winton

This study shows that phosphorylation of Atoh1 is essential for secretory progenitor plasticity and tissue regeneration in the intestine.

bioRxiv · Feb 26, 2018Cell Biology