Cancer BiologybioRxiv
Heterogeneity in clone dynamics within and adjacent to intestinal tumours identified by Dre-mediated lineage tracing
A.-S. K. Thorsen, D. Khamis, R. Kemp…·D. Winton
The paper uses Dre-mediated lineage tracing to study clone dynamics in intestinal tumours and adjacent tissue, revealing heterogeneous clonal expansion patterns and a zone of inhibited clone growth near tumours.
DOI 10.1242/dmm.046706