Synthetic budding morphogenesis by optogenetic receptor tyrosine kinase signaling
Louis S. Prahl, Ronald Canlla, Aria Zheyuan Huang, Daniel Alber, Sandra L. Shefter, Sachin Davis, Samuel H. Grindel, Zikang Dennis Huang, Thomas R. Mumford, William K. J. Benman, Lukasz J. Bugaj, Kyle W. McCracken, Alex J. Hughes
This paper uses optogenetic control of RET signaling to induce controlled budding in human kidney organoids.
bioRxiv · Apr 2, 2026 · PreprintBioengineering