Author

Daniel K. Sunderland

Jackson Laboratory

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Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Aakriti Bhandari· 1 shared Graham Clark· 1 shared Krishnakumar KizhatiliD· 1 shared Logan J. Horbal· 1 shared Revathi BalasubramanianiD· 1 shared Simon W. M. JohniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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1 shared paperCell Biology

Aakriti Bhandari

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1 paper

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedJan 2, 2025

FYN regulates aqueous humor outflow and IOP through the phosphorylation of VE-cadherin

Krishnakumar Kizhatil, Graham Clark, Daniel K. Sunderland…·Simon W. M. John

This study shows that FYN phosphorylates VE-cadherin in Schlemm's canal endothelial cells, increasing AJ permeability and reducing aqueous humor outflow resistance under elevated IOP.

5 citations

mouseexperimental assay

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