MicrobiologybioRxivPreprint
Dual inhibition of coronavirus Mpro and PLpro enzymes by phenothiazines and their antiviral activity
Katrina Forrestall, Eric S. Pringle, Dane Sands…·Sultan Darvesh
This paper identifies a phenothiazine urea derivative that inhibits both SARS-CoV-2 Mpro and PLpro proteases and shows broad antiviral activity against multiple human coronaviruses.
DOI 10.1101/2023.09.11.557219