PhysiologybioRxivPreprint
GPR35 inhibits TRPA1-mediated colonic afferent hypersensitivity through suppression of Substance P release
Rohit A Gupta, James P Higham, Paulina Urriola-Muñoz…·David C Bulmer
This paper identifies GPR35 as a target for non-opioid analgesics by showing it inhibits TRPA1-mediated colonic hypersensitivity through suppression of Substance P release.
DOI 10.1101/2023.09.12.557415