Cancer BiologyMolecular Therapy — Nucleic AcidsPeer-reviewed
Local Delivery of SBRT and IL12 by mRNA Technology Overcomes Immunosuppressive Barriers to Eliminate Pancreatic Cancer
Angela L. Hughson, Gary Hannon, N. A. Salama…·Scott A. Gerber
This paper demonstrates a combination treatment of SBRT and IL-12 mRNA in murine pancreatic tumors, achieving cures in both primary and metastatic models by enhancing T cell responses.
22 citations