Cell BiologyXenotransplantationPeer-reviewed
Generation of cloned sheep lacking galactose-α1,3-galactose and Nglycolylneuraminic acid antigens
Sarah Jane Appleby, LM Fermin, Zachariah L. McLean…·Björn J. Oback
This paper generates cloned sheep lacking two xenoantigens, Gal and Neu5Gc, by knocking out their respective genes, creating a model that better mimics human immune status for preclinical testing.
DOI 10.1111/xen.70134