GeneticsG3 Genes Genomes GeneticsPeer-reviewed
Demonstration of in vivo engineered tandem duplications of varying sizes using CRISPR and recombinases in Drosophila melanogaster
David W. Loehlin, Georgia L. McClain, Manting Xu…·Elise Root
The paper introduces a method to engineer tandem duplications in Drosophila using CRISPR and recombinases, showing increased ADH enzyme activity with varying duplication sizes.