Author

Debbie Piktel

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

John M. Hollander· 1 shared Karen H. Martin· 1 shared Laura F. Gibson· 1 shared Patrick Thomas· 1 shared Pushkar Saralkar· 1 shared Quincy A. Hathaway· 1 shared Rajesh R. Nair· 1 shared Stephanie L. Rellick· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

John M. Hollander

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintApr 1, 2019

Targeting the dysfunctional mitochondrial respiration in drug resistant B-cell acute lymphoblastic leukemia

Rajesh R. Nair, Debbie Piktel, Patrick Thomas…·Laura F. Gibson

This study identifies mitochondrial respiration dysfunction in drug-resistant ALL cells and shows that pyrvinium pamoate (PP) effectively targets this pathway, with enhanced bioavailability and specificity for leukemic cells.

DOI 10.1101/595959

humanbulk RNA-seq

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