Author

Despoina Despotopoulou

Institut Català de Nanociència i Nanotecnologia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Kostas KostarelosiD· 2 shared Maria StylianouiD· 2 shared Neus LozanoiD· 2 shared Thomas KisbyiD· 2 shared Alexandra Thawley· 1 shared Andrew S. MacDonaldiD· 1 shared Helen ParkeriD· 1 shared Kiana Arashvand· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 32 mutual co-author links

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2 shared papersBioengineering

Kostas KostarelosORCID

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2 papers

Recent·Most cited

BioengineeringJournal of Materials Chemistry BPeer-reviewedJan 1, 2025

Engineering of a graphene oxide-based two-dimensional platform for immune activation and modulation

Despoina Despotopoulou, Maria Stylianou, Luis M. Arellano…·Kostas Kostarelos

This study designs graphene oxide-based nanosheets to form stable complexes with the TLR7/8 agonist R848, preserving its biological activity and demonstrating effective macrophage activation.

3 citations

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BioengineeringCell Reports Physical SciencePeer-reviewedDec 18, 2024

Engineering the glioblastoma microenvironment using TLR7/8 agonist-complexed graphene oxide nanosheets

Maria Stylianou, Thomas Kisby, Despoina Despotopoulou…·Kostas Kostarelos

This paper demonstrates that graphene oxide nanosheets loaded with a TLR7/8 agonist can reprogram tumor-associated macrophages in GBM to a pro-inflammatory state, reducing tumor burden.

8 citations

mouseproteomics

𝕏 PostBluesky