Difei Hu

This study shows that unwinding RNA G-quadruplexes with FC3 induces and maintains totipotency in mouse and human cells, recapitulating 2-cell-stage features and enabling differentiation into embryonic and extraembryonic lineages.

This paper identifies a genomic mutation in monkeypox virus linked to increased transmission by analyzing the evolution of a G-quadruplex structure in the C9L gene.