PhysiologyNature Cardiovascular ResearchPeer-reviewed
Cardiomyocyte PGC-1α enables physiological adaptations to endurance exercise through suppression of GDF15 and cardiac atrophy
Sumeet A. Khetarpal, Haobo Li, Tevis Vitale…·Anthony Rosenzweig
This study shows that cardiomyocyte PGC-1α is essential for cardiac adaptation to endurance exercise by suppressing GDF15 and preventing cardiac atrophy in mice.
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