Author

Dinesh Manandhar

Duke University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Ami M. KabadiiD· 1 shared Amy SchmidiD· 1 shared Barbara Elizabeth EngelhardtiD· 1 shared Charles A. GersbachiD· 1 shared Christopher M. VockleyiD· 1 shared Gregory E. CrawfordiD· 1 shared Ian C. McDowelliD· 1 shared Jennifer B. Kwon· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Ami M. KabadiORCID

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2 papers

Recent·Most cited

BioinformaticsPLoS Computational BiologyPeer-reviewedJan 16, 2018

Clustering gene expression time series data using an infinite Gaussian process mixture model

Ian C. McDowell, Dinesh Manandhar, Christopher M. Vockley…·Barbara Elizabeth Engelhardt

This paper introduces a nonparametric model, DPGP, to cluster gene expression time series data and demonstrates its effectiveness using simulated and real datasets.

193 citationstop 2%

humanmouse

𝕏 PostBluesky

GenomicsNucleic Acids ResearchPeer-reviewedAug 28, 2017

Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies

Dinesh Manandhar, Lingyun Song, Ami M. Kabadi…·Raluca Gordân

The paper quantifies incomplete gene expression and chromatin accessibility changes during MyoD-induced transdifferentiation of human fibroblasts into myoblasts, linking chromatin remodeling deficiencies to incomplete reprogramming.

34 citations

humanbulk RNA-seq

𝕏 PostBluesky