Author

E. Andrzejewska

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

M. Vendruscolo· 2 shared A. Aubert· 1 shared A. J. Dear· 1 shared A. Possenti· 1 shared A. Srivastava· 1 shared B. Caughey· 1 shared B. Ghetti· 1 shared C. K. Xu· 1 shared

Activity by Year

2021-2024 · peak 1/yr

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10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

M. Vendruscolo

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2 papers

Recent·Most cited

BiophysicsNature CommunicationsPeer-reviewedAug 17, 2024

α-Synuclein oligomers form by secondary nucleation

C. K. Xu, G. Meisl, E. Andrzejewska…·T. P. Knowles

This study shows α-synuclein oligomers form via secondary nucleation on fibril surfaces, not from monomers, and this process is enhanced by agitation under physiological conditions.

DOI 10.1038/s41467-024-50692-4

experimental assay

𝕏 PostBluesky

BiophysicsbioRxivNov 10, 2021

Discovery of Potent Inhibitors of α-Synuclein Aggregation Using Structure-Based Iterative Learning

R. I. Horne, E. Andrzejewska, P. Alam…·M. Vendruscolo

This paper uses structure-based machine learning to identify potent small molecule inhibitors of α-synuclein aggregation, achieving compounds two orders of magnitude more potent than previous reports.

DOI 10.1038/s41589-024-01580-x

deep learningdrug response / drug discovery

𝕏 PostBluesky