Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis product
A. Mishra, S.-B. Huang, T. Dubash, R. Burr, B. S. Wittner, Q. E. Cunneely, V. R. Putaturo, A. Deshpande, E. Antmen, K. A. Gopinathan, K. Otani, Y. Miyazawa, J. E. Kwak, S. Y. Guay, J. Kelly, , M. Toner
This study uses high-throughput microfluidic technology to enrich CTCs from large blood volumes, enabling detailed molecular and morphological analysis of tumor cells in metastatic cancer patients.
bioRxiv · Mar 13, 2024 · PreprintBioengineering