Author

E. Bono

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:protein sequence· 1 Organism:rat· 1

Frequent Co-Authors

D. Marotta· 3 shared L. Donnici· 3 shared M. Rava· 3 shared P. Di Lucia· 3 shared V. Fumagalli· 3 shared C. Perucchini· 2 shared E. Sala· 2 shared L. Giustini· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

D. Marotta

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Nirmatrelvir treatment blunts the development of antiviral adaptive immune responses in SARS-CoV-2 infected mice

V. Fumagalli, P. Di Lucia, M. Rava, D. Marotta, E. Bono, S. Grassi, L. Donnici, R. Cannalire, I. Stefanelli, A. Ferraro, F. Esposito, E. Pariani, D. Inverso, C. Montesano, S. Delbue, , M. Iannacone

This study shows that nirmatrelvir treatment in SARS-CoV-2 infected mice reduces antibody and T cell responses, leading to weaker memory cell recruitment upon secondary challenge.

bioRxiv · Nov 22, 2022Immunology

Controlled administration of aerosolized SARS-CoV-2 to K18-hACE2 transgenic mice uncouples respiratory infection and anosmia from fatal neuroinvasion

V. Fumagalli, M. Rava, D. Marotta, P. Di Lucia, C. Laura, E. Sala, M. Grillo, E. Bono, L. Giustini, C. Perucchini, M. Mainetti, A. Sessa, J. Garcia-Manteiga, L. Donnici, L. Manganaro, , M. Iannacone

This study develops an aerosolized SARS-CoV-2 infection model in K18-hACE2 mice that replicates respiratory symptoms without fatal neuroinvasion, offering a more accurate representation of human COVID-19 pathogenesis.

bioRxiv · Aug 6, 2021Immunology

COVID-eVax, an electroporated plasmid DNA vaccine candidate encoding the SARS-CoV-2 Receptor Binding Domain, elicits protective immune responses in animal models of COVID-19

A. Conforti, E. Marra, F. Palombo, G. Roscilli, M. Rava, V. Fumagalli, A. Muzi, M. Maffei, L. Luberto, L. Lione, E. Salvatori, M. Compagnone, E. Pinto, E. Pavoni, F. Bucci, , De F

This paper evaluates a DNA vaccine candidate, COVID-eVax, which induces strong neutralizing antibodies and T cell responses against SARS-CoV-2 in animal models, showing protective effects against viral challenge.

bioRxiv · Jun 14, 2021 · PreprintImmunology