ImmunologybioRxiv
GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma
T. Gargett, L. M. Ebert, N. T. H. Truong…·M. P. Brown
This study demonstrates that GD2-targeting CAR-T cells, enhanced with IL-15 transgene expression, effectively control glioblastoma growth in a preclinical model and are clinically feasible.
DOI 10.1136/jitc-2022-005187