Author

E. C. Farrell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. J. Knights· 2 shared O. M. Ellis· 2 shared T. Maerz· 2 shared A. A. Samani· 1 shared C. T. Appleton· 1 shared C.-L. Wu· 1 shared K. D. Hankenson· 1 shared L. Lammlin· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

A. J. Knights

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Author profile →

2 papers

Recent·Most cited

Synovial macrophage diversity and activation of M-CSF signaling in post-traumatic osteoarthritis

A. J. Knights, E. C. Farrell, O. M. Ellis, M. J. Song, C. T. Appleton, T. Maerz

This study identifies synovial macrophage subpopulations and their regulation by M-CSF signaling in a mouse model of post-traumatic osteoarthritis.

bioRxiv · Oct 3, 2023Immunology

Synovial fibroblasts assume distinct functional identities and secrete R-spondin 2 to drive osteoarthritis

A. J. Knights, E. C. Farrell, O. M. Ellis, L. Lammlin, L. M. Junginger, P. M. Rzeczycki, R. F. Bergman, R. Pervez, M. Cruz, A. A. Samani, C.-L. Wu, K. D. Hankenson, T. Maerz

This study identifies distinct synovial fibroblast subsets in PTOA and shows that Prg4hi fibroblasts secrete Rspo2 to drive pathological crosstalk.

bioRxiv · May 6, 2022 · PreprintCell Biology