Cell BiologybioRxivPreprint
Synovial fibroblasts assume distinct functional identities and secrete R-spondin 2 to drive osteoarthritis
A. J. Knights, E. C. Farrell, O. M. Ellis…·T. Maerz
This study identifies distinct synovial fibroblast subsets in PTOA and shows that Prg4hi fibroblasts secrete Rspo2 to drive pathological crosstalk.