Sexual dimorphism of the synovial transcriptome underpins greater PTOA disease severity in male mice following joint injury
R. F. Bergman, L. Lammlin, L. Junginger, E. Farrell, S. Goldman, R. Darcy, C. Rasner, A. M. Obeidat, A.-M. Malfait, R. Miller, T. Maerz
This study shows male mice have worse joint damage and persistent synovial inflammation after ACLR injury compared to females.
bioRxiv · Nov 30, 2022Physiology