Radiation therapy promotes unsaturated fatty acids to maintain survival of glioblastoma
M. De Martino, C. Daviaud, H. E. Minns, N. Attarwala, Q. Chen, N. Dephoure, S.-W. Choi, R. Rabadan, R. D. Gartrell, E. C. Laiakis, C. Vanpouille-Box
This study shows that radiation therapy promotes unsaturated fatty acid accumulation in glioblastoma, enhancing survival by reducing ER stress, and that targeting lipid metabolism could improve treatment outcomes.
bioRxiv · Jun 1, 2022Cell Biology