The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice
I. Ullah, G. Beaudoin-Bussieres, K. Symmes, M. Cloutier, E. Ducas, A. Tauzin, A. Laumaea, P. Begin, W. Mothes, R. Bazin, A. Finzi, P. D. Uchil
This study shows that CCPs with high Fc-effector activity, rather than just neutralizing ability, are more effective in treating SARS-CoV-2 in mice.
bioRxiv · Jun 10, 2022Immunology