Author

E. Dumont

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Biophysics· 4 Animal Behavior & Cognition· 1 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 4 Assay:DNA methylation· 4 Research Focus:protein folding & dynamics· 4 Organism:human· 3 Approach:mechanistic / dynamical model· 3 Approach:statistical model· 3 Approach:biophysical modeling· 2 Approach:experimental assay· 2

Frequent Co-Authors

E. Bignon· 8 shared A. Monari· 6 shared T. Jiang· 5 shared N. Gillet· 4 shared C. Morell· 2 shared V. Claerbout· 2 shared A. A. Sadier· 1 shared A. Chopo Pizzaro· 1 shared

Activity by Year

2020-2024 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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8 shared papersBiophysics

E. Bignon

Mutual co-authors in cluster

Author profile →

11 papers

Recent·Most cited

Behavioural Investigations of Psilocybin in Animals 1962-2021: A Scoping Review

R. J. Shore, K. Dobson, N. Thomson, N. Barnim, H. Bergman, K. Rideout, S. Mckeown, M. Olmstead, C. Goldie, E. Dumont

This paper reviews pre-clinical behavioral studies of psilocybin in non-human animals from 1962-2021, identifying behavioral effects, tests used, and dosing modalities.

bioRxiv · Jan 4, 2024 · PreprintAnimal Behavior & Cognition

Novel hypervariable erythrocyte surface expressed recombinant proteins show promise as serological markers of exposure to Plasmodium falciparum infection.

H. Vasileva, A. Chopo Pizzaro, M. Ooko, E. Dumont, L. Wu, I. Ssewanyana, A. Last, K. Tetteh

The paper expresses STEVOR and RIFIN recombinant proteins from Plasmodium falciparum and evaluates their seropositivity in Ugandan cohorts to assess their potential as infection markers.

bioRxiv · Oct 31, 2023 · PreprintImmunology

How SARS-CoV-2 alters the regulation of gene expression in infected cells.

E. Bignon, S. Grandemange, E. Dumont, A. Monari

This study uses molecular dynamics simulations to show how SARS-CoV-2 ORF8 protein interacts with DNA via a histone-like motif, affecting epigenetic regulation and potentially informing antiviral strategies.

bioRxiv · Dec 18, 2022Biophysics

Molecular basis of the pH-controlled maturation of the tick-borne encephalitis flavivirus

E. Bignon, E. Dumont, A. MONARI

The paper investigates the pH-dependent maturation of the tick-borne encephalitis flavivirus's E protein, revealing how pH affects dimer stabilization and the role of the pr protomer.

bioRxiv · Oct 27, 2022Biophysics

Molecular mechanisms associated with clustered lesion-induced impairment of 8-oxoG recognition by the human glycosylase OGG1

T. Jiang, A. MONARI, E. Dumont, E. Bignon

This study investigates how clustered 8-oxoG lesions affect hOGG1 recognition using molecular dynamics and machine learning, finding that mismatches reduce repair efficiency by altering 8-oxoG structure.

bioRxiv · Sep 23, 2021Biophysics

Ecological constraints on highly evolvable olfactory receptor genes and morphology

L. R. Yohe, M. Fabbri, D. Lee, K. Davies, T. P. Yohe, M. K. Sanchez, E. Rengifo, R. Hall, G. Mutumi, B. P. Hedrick, A. A. Sadier, N. B. Simmons, K. E. Sears, E. Dumont, S. Rossiter, , L. Davalos

The paper examines how ecological factors influence the evolution of olfactory receptor genes and morphology in bats, finding that increased reliance on olfaction correlates with reduced genetic diversity in these genes.

bioRxiv · Sep 6, 2021 · PreprintEvolutionary Biology

How fragile we are. Influence of STimulator of INterferon Genes, STING, variants on pathogen recognition and immune response efficiency

J. Morere, C. Hognon, T. Miclot, T. Jiang, E. Dumont, G. Barone, E. Bignon, A. MONARI

The paper uses molecular simulations and machine learning to analyze STING variants and explains how structural changes affect immune response efficiency.

bioRxiv · Jul 12, 2021Biochemistry

A dynamic view of histone tails interaction with clustered abasic sites in a nucleosome core particle

E. Bignon, N. Gillet, T. Jiang, C. Morell, E. Dumont

The paper investigates the structural behavior of clustered abasic sites in a nucleosome core particle using molecular dynamics simulations and identifies key histone residues involved in DNA-protein cross-linking.

bioRxiv · Feb 16, 2021Biochemistry

Recognition of a Tandem Lesion by DNA Glycosylases Explored Combining Molecular Dynamics and Machine Learning

E. Bignon, N. Gillet, C.-H. Chan, T. Jiang, A. Monari, E. Dumont

This study uses molecular dynamics and machine learning to analyze how DNA glycosylase MutM recognizes tandem lesions versus single lesions in DNA.

bioRxiv · Jan 6, 2021Biochemistry

Impact of the nucleosome histone core on the structure and dynamics of DNA containing pyrimidine-pyrimidone (6-4) photoproduct

E. Matouskova, E. Bignon, V. Claerbout, T. Drsata, N. Gillet, A. MONARI, E. Dumont, F. Lankas

The paper uses molecular dynamics simulations to study how the nucleosome histone core affects DNA structure and dynamics with 64-PP lesions, showing increased local flexibility and potential repair recognition signals.

bioRxiv · Apr 24, 2020Biophysics

Nucleosomal embedding reshapes the dynamics of abasic sites

E. Bignon, V. Claerbout, T. Jiang, C. Morell, N. Gillet, E. Dumont

This study uses molecular dynamics simulations to show how AP sites in nucleosomal DNA exhibit distinct dynamics and increased DNA-protein cross-link formation compared to tetrahydrofuran analogs.

bioRxiv · Feb 26, 2020Biochemistry