HIV-1 Vpr causes separate cell cycle arrests in G2 and M that activate alternative DNA damage pathways
R. Hall, L. M. Ahern, M. W. Yap, M.-H. C. Tsai, V. C. Boucherit, T. Takaki, S. J. Boulton, K. N. Bishop
This paper shows HIV-1 Vpr causes separate G2 and M phase cell cycle arrests that activate distinct DNA damage pathways, with implications for early HIV replication.
bioRxiv · Apr 2, 2024 · PreprintMicrobiology