Cell dichotomous role of STING in pulmonary hypertension
A. T. Pham, A. C. Oliveira, C. Fu, M. D. Alves, Z. Dupee, L. Mukhsinova, E. Ebrahimi, H. Patel, R. Patel, A. Nguyen, l. jin, A. J. Bryant
This study investigates the role of STING in pulmonary hypertension, finding that STING overactivation contributes to disease while global deficiency protects against it, with distinct cellular roles in smooth muscle and myeloid cells.
bioRxiv · Nov 29, 2022 · PreprintImmunology