Cancer BiologybioRxivPreprint
β-catenin obstructs γδ T cell immunosurveillance in colon cancer through loss of BTNL expression
T. Suzuki, A. Kilbey, R. A. Ridgway…·S. B. Coffelt
This study shows that β-catenin signaling in colon cancer cells reduces BTNL expression, impairing γδ T cell immunosurveillance and promoting tumor progression.