Author

E. Gorbunova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

E. R. Mackow· 3 shared W. R. Schutt· 3 shared G. Himmler· 2 shared H. K. Kim· 2 shared J. N. Conde· 2 shared B. Altaha· 1 shared D. Haller· 1 shared H. Oster· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

E. R. Mackow

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Age-dependent Powassan Virus Lethality is Directed by Glial Cell Activation and Divergent Neuroinflammatory Cytokine Responses in a Murine Model

M. C. Mladinich, G. Himmler, J. N. Conde, E. Gorbunova, W. R. Schutt, S. Sarkar, S.-A. Tsirka, H. K. Kim, E. R. Mackow

This study establishes a murine model of age-dependent Powassan virus (POWV) lethality, revealing divergent neuroinflammatory cytokine responses in young and old mice that correlate with CNS viral clearance and disease severity.

bioRxiv · Dec 18, 2023 · PreprintMicrobiology

Age-dependent Powassan Virus Lethality and Neuropathogenesis in Mice

M. Mladinich, G. Himmler, J. N. Conde, E. Gorbunova, W. R. Schutt, S. Tsirka, H. K. Kim, E. R. Mackow

This study shows that older mice are more susceptible to lethal Powassan virus infection, with increased viral load and severe brain damage compared to younger mice.

bioRxiv · May 11, 2023 · PreprintMicrobiology

Genetic and environmental circadian disruption induce metabolic impairment through changes in the gut microbiome

B. Altaha, M. Heddes, V. Pilorz, Y. Niu, E. Gorbunova, M. Gigl, K. Kleigrewe, H. Oster, D. Haller, S. Kiessling

This study shows that circadian disruption from genetic and environmental factors causes metabolic issues by altering gut microbiome function and rhythmicity.

bioRxiv · Jul 27, 2022 · PreprintPhysiology

Recombinant ACE2 Expression is Required for SARS-CoV-2 to Infect Primary Human Endothelial Cells and Induce Inflammatory and Procoagulative Responses

J. Nascimento Conde, W. R. Schutt, E. Gorbunova, E. R. Mackow

This study shows that SARS-CoV-2 cannot directly infect primary human endothelial cells without recombinant ACE2 expression, but infection of ACE2-expressing endothelial cells induces inflammatory and procoagulative responses seen in COVID-19.

bioRxiv · Nov 10, 2020Microbiology