Author

E. Guney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. P. Arruda· 2 shared E. Cagampan· 2 shared G. Parlakgul· 2 shared G. S. Hotamisligil· 2 shared Y. Lee· 2 shared B. van de Water· 1 shared C. S. Xu· 1 shared E. Tsaousidou· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

A. P. Arruda

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Author profile →

3 papers

Recent·Most cited

The human hepatocyte TXG-MAPr: WGCNA transcriptomic modules to support mechanism-based risk assessment

G. Callegaro, S. J. Kunnen, P. Trairatphisan, S. Grosdidier, M. Niemeijer, W. den Hollander, E. Guney, J. P. Gonzalez, L. Furlong, Y. W. Webster, J. Saez-Rodriguez, J. J. Sutherland, J. Mollon, J. L. Stevens, B. van de Water

The paper introduces TXG-MAPr, a tool for analyzing toxicogenomic data using WGCNA to identify stress response modules across species and platforms.

bioRxiv · May 17, 2021Pharmacology & Toxicology

High resolution 3D imaging of liver reveals a central role for subcellular architectural organization in metabolism

G. Parlakgul, A. P. Arruda, E. Cagampan, S. Pang, E. Guney, Y. Lee, H. F. Hess, C. S. Xu, G. S. Hotamisligil

The paper uses high-resolution 3D imaging to show that subcellular organization in liver cells changes with obesity, affecting metabolism.

bioRxiv · Nov 18, 2020Cell Biology

Aberrant Ca2+ homeostasis in adipocytes links inflammation to metabolic dysregulation in obesity

E. Guney, A. P. Arruda, G. Parlakgul, E. Cagampan, N. Min, Y. Lee, L. Greene, E. Tsaousidou, K. Inouye, M. S. Han, R. J. Davis, G. S. Hotamisligil

This study identifies IP3R over-activation in adipocytes as a key mechanism linking obesity, inflammation, and insulin resistance, suggesting therapeutic targeting of Ca2+ homeostasis.

bioRxiv · Oct 28, 2020Physiology