Cancer BiologybioRxiv
RHAMMB-mediated bifunctional nanotherapy targeting Bcl-xL and mitochondria for pancreatic neuroendocrine tumor treatment
X. Chen, S. K. Lee, M. Song…·Y.-C. N. Du
This paper develops a RHAMMB-targeting nanoparticle delivering siBcl-xL and KLA peptide to treat PNETs, showing synergistic tumor reduction in mice.
DOI 10.1016/j.omto.2021.10.002