BiochemistrybioRxivPreprint
Engineered Antigen-Binding Fragments for Enhanced Crystallisation of Antibody:Antigen Complexes
H. A. Bruce, A. U. Singer, E. V. Filippova…·S. S. Sidhu
This study identifies surface substitutions that enhance the crystallisation of Fab:antigen complexes by combining surface entropy reduction with phage-display technology and previously reported substitutions.
DOI 10.1101/2023.07.06.548021