Identification of a Novel Susceptibility Marker for SARS-CoV-2 Infection in Human Subjects and Risk Mitigation with a Clinically Approved JAK Inhibitor in Human/Mouse Cells
M. R. Spalinger, R. Hai, J. Li, A. N. Santos, T. M. Nordgren, M. L. Tremblay, L. Eckmann, E. Hanson, M. Scharl, X. Wu, B. S. Boland, D. F. McCole
The paper identifies a genetic variant that increases SARS-CoV-2 receptor expression and susceptibility, and shows a JAK inhibitor reduces this risk.
bioRxiv · Dec 9, 2020 · PreprintMicrobiology