Knockout of Anopheles stephensi immune gene LRIM1 by CRISPR-Cas9 reveals its unexpected role in reproduction and vector competence
E. Inbar, A. Eappen, R. T. Alford, W. Reid, R. A. Harrell, M. Hosseini, S. Chakravarty, T. Li, B. K. L. Sim, P. F. Billingsley, S. L. Hoffman
This study shows that knocking out LRIM1 in Anopheles stephensi mosquitoes disrupts microbiome balance, reduces vector competence, and affects reproductive traits.
bioRxiv · Jul 2, 2021Microbiology