S. Chakravarty

Multiomics analysis reveals B. MO1 as a distinct Babesia species and provides insights into its evolution and virulence.

The paper identifies B. MO1 as a distinct Babesia species through multiomics analysis, revealing genomic and functional differences from B. divergens and insights into their evolution and virulence.

Incorporating Radiopacity into Implantable Polymeric Biomedical Devices for Clinical Radiological Monitoring

This study evaluates radiopaque polymeric biomedical devices containing TaOx nanoparticles, showing they maintain structural integrity and radiopacity over 20 weeks in vitro and in vivo.

Mathematical bridge between epidemiological and molecular data on cancer and beyond

The paper develops a mathematical framework integrating epidemiological and molecular data on cancer and tests it against non-neoplastic conditions.

Decoding The Nuclear Genome of The Human Pathogen Babesia duncani Shed Light on its Virulence, Drug Susceptibility and Evolution among Apicomplexa

This study decodes the nuclear genome of Babesia duncani, identifies virulence factors and drug targets, and discovers potent inhibitors for treating babesiosis.

Closed-Loop Control of Anesthetic State in Non-Human Primates

This paper develops and validates a closed-loop anesthesia delivery system in rhesus macaques using EEG signals to control propofol infusion and maintain unconsciousness.

Clonal evolution and specificity of the human T follicular helper cell response to Plasmodium falciparum circumsporozoite protein

This study examines the clonal evolution and TCR specificity of human TFH cells responding to PfCSP during malaria immunization, revealing HLA restrictions and epitope-specific dynamics.

Knockout of Anopheles stephensi immune gene LRIM1 by CRISPR-Cas9 reveals its unexpected role in reproduction and vector competence

This study shows that knocking out LRIM1 in Anopheles stephensi mosquitoes disrupts microbiome balance, reduces vector competence, and affects reproductive traits.

Mapping of safe and early chemo-attenuated live Plasmodium falciparum immunization identifies immune signature of vaccine efficacy

This study evaluates the safety and efficacy of chemo-attenuated Plasmodium falciparum immunization, identifying immune signatures that correlate with vaccine protection.

Atypical B cells are a normal component of immune responses to vaccination and infection in humans

This study identifies atypical B cells as a normal part of immune responses to vaccination and infection in humans, showing they are present in both malaria-exposed and healthy individuals.

Antibody feedback limits the expansion of cognate memory B cells but drives the diversification of vaccine-induced antibody responses

The paper shows antibody feedback limits memory B cell expansion but allows diversification of vaccine-induced antibody responses by suppressing dominant epitopes while enabling subdominant ones.

A simple and sensitive SYBR Gold-based assay to quantify DNA-protein interactions

The paper develops a SYBR Gold-based assay to quantify DNA-protein interactions, showing distinct binding affinities of ARF transcription factors to AuxRE motifs.